I taught two sections of a course last semester, one MWF (50 mins each) and one TuTh (75 mins each). It was not great.
The main problem is not even splitting material across days. It's an issue of timing and attention. It takes much more effort on the teacher's part, both pre- and during class, to effectively engage for 75 mins. I found myself planning different activities and group work, or sometimes letting them run longer in the 75 min section. I don't think even that was good enough.
Honestly, the best thing to do is make a list of the major concepts and activities from the course and plot your days around that list. With a TuTh course, you might have to cut two or three ideas over the course of a semester, but you can give a fuller treatment of the others. For instance, with your Stewart calculus course, identify a handful of sections that could feasibly be skipped, or at least covered only cursorily. Allow yourself more time for each of the ideas you have left and work in some extra in-class activities.